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What is Massive bilateral myoclonus?

     

Massive bilateral myoclonus is a type of generalized seizures. upper limbs, elevation of the shoulders which gives contraction to the chest is mainly involved in massive bilateral myoclonus. Massive bilateral myoclonus can be asymmetrical and twitches are increased with waking up and fall sleeping.

Diseases related to Massive bilateral myoclonus

Following are some diseases or syndromes in which massive bilateral myoclonus occur.

  1. Benign myoclonic epilepsy
  2. Dravet syndrome
  3. Myoclonic-astatic epilepsy.

What are the symptoms of Massive bilateral myoclonus?

  • Patients may drop objects from hand or
  • Patients may fall on ground but it is very rare.

How diagnosis of Massive bilateral myoclonus done?

  • Myoclonic-astatic seizures and spasms may look like massive bilateral myoclonus. so it is important to diagnosed massive bilateral myoclonus clearly.
  • EEG recording combined with EMG recording
  • Awake and sleep recording are needed.

What is treatment for Massive bilateral myoclonus?

  1. Valproate is mainly used juvenile myoclonic epilepsy and benign myoclonic epilepsy in infancy.
  2. Lamotrigine, topiramate, levetiracetam and ethosuximide are also preferred for treatment.