How to Get Rid of Cri du chat Syndrome

Information of Cri du chat Syndrome

Cri du chat syndrome is widely known as an autosomal deletion syndrome. It is of genetic nature. This syndrome results from a partial missing short arm of chromosome number 5. The name of Cri du chat syndrome is derived from the fact that the characteristic Cry of infants is similar to the mewing of baby cat (kittens).

The abnormal larynx and other central nervous system disorders are responsible for the cat like cry in infants. Most infants and children with Cri du chat syndrome die in early childhood.

Cause of Cri du chat Syndrome

The main cause of Cri du chat syndrome is missing arm of chromosome 5.

• The cause of Cri du chat syndrome is genetic. The cause of cri du chat syndrome is partial deletion of information on chromosome 5. Sometimes multiple genes on chromosome 5 may be missing.
• In most of the cases, deleted chromosome is from paternal side.
• The deleted chromose 5 may vary from one arm to a small portion known as 5p15. In most of the cases around 30 to 60% of the arm of chromosomes is deleted.
• Telomerase reverse transcriptase gene is responsible for cell growth, if found missing, may develop symptoms characteristics to abnormal growth.
• The probablity of Cri du chat syndrome is pretty less. The risk of affecting cri du chat syndrome affects one in around 50,000 births. These babies can be diagnosed for cri du chat syndrome b