Uses and side effects of ErgotamineTweet
Ergotamine should be used in patients not benefited by simple. If given early in attack, relief is often dramatic and lower doses suffice. It is a potent vasoconstrictor and also has alpha- adrenergic blocking action. It is used in the acute management of migraine and related vascular headaches but not for prophylaxis.
Migraine, cluster headache and vascular headache.
1 mg is given at half hour intervals till relief is obtained. Maximum: 6mg.
Coronary, peripheral or occlusive vascular disease. Severe hypertension, coronary artery disease. Impaired hepatic or renal functions. Pregnancy, lactation, septic conditions.
Special precautions while taking Ergotamine
Do not exceed the indicated dose.
Pediatrics: Not usually prescribed
Pregnancy: Not usually prescribed
Lactation: not recommended
Elderly: use with caution.
Side effects of Ergotamine
Nausea, vomiting. GI disturbances, pallor, coldness and tingling of the extremities.
Ergotamine Drug interaction
Smoking, beta-blockers and methylsergide increases risk of vascular occlusion. Simultaneous use of oral contraceptives increase risk of thrombosis. Erythromycin increases plasma concentration of Ergotamine.