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Sumatriptan is a specific and selective 5-hydroxytryptamine 1-like (5HT 1-like) receptor agonist with little or no effect at a variety of other receptor types. It produces a dose-related vasoconstriction in the cerebral circulation. It does not bind to alpha adrenergic, beta adrenergic, mucarinic, dopaminergic or benzodiazepine receptors. It provides relief in both the headache and other symptom such as nausea and photophobia.
Sumatriptan Indication
Acute treatment for migraine, severe acute pain of a cluster headache attack.
Dosage of Sumatriptan
50 mg - 300 mg in 24 hours or as directed by physician.
Sumatriptan Contraindication
Ischemic heart disease, hypertension.
Special precaution while taking Sumatriptan
Should not be given intravenously in patients with ischemic heart disease, hepatic impairment.
Pediatrics: Not recommended
Pregnancy: Should not be used
Lactation: Should not be used
Elderly: Use with caution. Not recommended in age above 65 years.
Side effects of Sumatriptan
Sudden wheeziness, fluttering or tightness in the chest, swelling of eyelids, face or lips, skin rash, red spots or hives.
Sumatriptan Drug interactions
Ergotamine, lithium and MAOIs increases the risk of side effects.
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| Depression Tip |
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If you are taking more than one medication, and at different times of the day, it is essential that you take the correct dosage of each medication.
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