Home Treatments Depression Medication  

Tenex antidepressants for ADHD | Side effects of Tenex or Guanfacine


Generic Name: Guanfacine
Brand Names: Tenex, Intunive, Estulic
Guanfacine is used widely to control the symptoms and treat ADHD in both Adults and Children.

Category: Antihypertensive

Uses of Tenex:

Tenex belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension) but that may also be helpful in reducing ADHD symptoms. Like another antihypertensive drug, Catapres etc. (Clonidine), Tenex regulates levels of the neurotransmitter norepinephrine and may be effective in reducing ADHD symptoms alone or in combination with stimulants. They also may be used as an alternative to stimulant medication, especially in the 30% of children who cannot tolerate stimulants and in children with conduct problems. However, antihypertensives may not improve attention deficit or distractibility. Tenex may also reduce symptoms of aggression and reduce the insomnia associated with stimulants.

Tenex works by controlling nerve impulses along certain nerve pathways. As a result, it relaxes blood vessels so that blood passes through them more easily. This helps to lower blood pressure.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Tenex for ADHD and Tics disorders like Tourette's syndrome

Tenex is pharmacologically similar to clonidine. In a controlled trial of children with ADHD plus tics like Tourette's syndrome, Tenex improved symptoms in both domains, though the improvements in attention fell short of what is generally seen with standard medications. Side effects are similar to those of clonidine, though Tenex is less sedating.

Research published in the Journal of Psychiatry (July, 2001) concluded that Tenex appears to be a safe and effective treatment for children with tic disorders and ADHD. In the study, Tenex was associated with a mean improvement of 37% in the total score on a teacher-rated ADHD Rating Scale, compared to 8% improvement for placebo after 8 weeks of treatment.

How to Take Tenex:

Take this medicine as directed. It can be taken with or without food. Do not stop taking this medicine abruptly without consulting with your doctor.

Some important information about Tenex or Intuniv

  1. Do not use these drugs if yor are allergic to Antihypertensive drugs. It is important to tell you doctor beforehand if you have any heart disease, low blood preussure, or kidney/liver disease.
  2. Do not consume alcohol and also do not indulge in rigourous exercise.
  3. Do not miss any visits with your doctor since it is vital to check the heart rate and blodd pressure on regular intervals if you are on Tenex or Intuniv.

How Tenex works?

Tenex lowers the blood pressure of the body by reducing the heart rate and relaxing the vessels. It is very important to inform the doctor if you have any heart diseases or conditions related to blood pressure. It need to be controlled if the person is on any heart rate stimulants or blood thinners.

Side Effects of Tenex:

Some common side effects reported with this medicine include:

  • difficulty breathing
  • closing of your throat
  • swelling of your lips, tongue, or face
  • hives
  • depression
  • very slow heart rate (fewer than 60 beats per minute)
  • unusually high or low blood pressure (fainting, a severe headache, flushing of your face)
  • unusual fatigue, dizziness, or tiredness
  • headache
  • dry mouth
  • constipation
  • insomnia
  • constipation, nausea, vomiting, or diarrhea

Warnings and precautions for Tenex

  • Do not take other medicines unless they have been discussed with your doctor . This especially includes over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood pressure.
  • Check with your doctor before you stop taking guanfacine. Your doctor may want you to reduce gradually the amount you are taking before stopping completely.
  • Tenex will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine .
  • Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine.
  • Make sure that you have enough guanfacine on hand to last through weekends, holidays, and vacations. You should not miss any doses. You may want to ask your doctor for another written prescription for guanfacine to carry in your wallet or purse. You can then have it filled if you run out when you are away from home.

What to do if you take Overdose of Tenex?

Seek medical attention immediately. For non emergencies, contact your local or regional poison control center.

What to do if you take Missed Dose of Tenex?

Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take a double dose to make up for a missed one.

How to Store Tenex:

Keep this medication in the container it came in, tightly closed, and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Sometimes crying or laughing
are the only options left,
and laughing feels better right now.

Stay Connected with DG


Current Issue

Self Help Leaflets

Take the help of our self help leaflets or booklets.

The DG Magazine

All about living with depression

Alphabatical list of Medicines